Tisseel Kit

The information contained in this page is intended for Indian healthcare professionals only.TISSEEL™ Kit consists of a two-component fibrin sealant offers highly concentrated human fibrinogen to seal tissue and stop diffuse bleeding.IndicationsTISSEEL™ KIT is used to achieve hemostasis, to seal or glue tissue, and to support wound healing. In certain applications biocompatible material, such as collagen fleece, is used as a carrier substance or for reinforcement.Indications include, but are not limited to:Hemostasis: Hemostasis in diffuse bleedings, after joint and bone surgery, adenoidectomy and tonsillectomy as well as after maxillodental surgery in patients with bleeding disorders, sealing of the prostatic bed after prostatectomy.Sealing: Coating and sealing of vascular prostheses, tympanoplasty, management of C.S.F. fistulae and dura lesions, treatment of premature rupture of the membranes in pregnancy by sealing of the lower amniotic region, air-tight sealing of sutures in lung parenchyma and pleura, of sutures in trachea, bronchus and oesophagus, management of malignant pleural effusion, sealing of the lens after injuries with perforations, sealing of suture lines to prevent leakage of intestinal anastomoses, additional sealing of sutured microvascular anastomoses, etc.Tissue gluing: Gluing of parenchyma in surgery on the kidney, liver, spleen and pancreas, spongiosa grafting when packing bone cavities and defects, pleurodesis in spontaneous pneumo thorax, fixation of skin grafts and flaps, fixation of osteochondral fragments and implants, gluing of peripheral nerves, plastic surgery after opening of the maxillary sinus etc.Support of Wound Healing: Skin grafting on devascularised and infected recipient sites, management of skin necrosis and mucosal ulcers, incorporation of homologous bone grafts.FeaturesUpon mixing Sealer Protein (Human) and Thrombin (Human), it quickly sets to form a white, elastic mass which firmly adheres to the tissue i.e., wound surface and achieves hemostasis and sealing or gluing of tissues1Fibrinogen is converted to fibrin strands that join into net-like matrices2In the course of wound healing the solidified fibrin sealant is completely absorbedSafety and EfficacyManufactured using processed,screened pooled human plasma, a vapor heating process, and a solvent detergent process1Satisfactory for use in fully heparinized patients undergoing cardiopulmonary bypass1Tisseel Kit can even be applied in fully heparinized patients(eg extracorporeal circulations)