Xbira 250 mg Tablets, For Hospital, Packaging Type: Bottle

Description: Xbira 250 mg tablet belongs to a class drugs known as antiandrogens. It stops the body from making testosterone which can slow the growth of prostate cancer.XBIRA 250mg – Abiraterone Acetate is a drug used in combination with prednisone in metastatic castration-resistant prostate cancer (formerly hormone-resistant prostate cancer) which is a prostate cancer not responding to androgen deprivation or treatment with anti-androgens.Abiraterone Acetate decreased serum testosterone and other androgens in patients in the placebo-controlled Phase 3 clinical trials. It is not necessary to monitor the effect of Abiraterone Acetate on serum testosterone levels. Changes in serum prostate-specific antigen (PSA) levels may be observed, but have not been shown to correlate with clinical benefit in individual patients. Common side effects: Anemia, Joint pain, Joint swelling, Cough, Shortness of breath, Hot flashes, Increased cholesterol level in blood, Increased glucose level in blood, Increased triglyceride level in blood, Decreased potassium level in blood, Increased blood pressure, Urinary tract infection, Weakness, Vomiting, Diarrhoea The recommended dose of XBIRA tablets is 1000mg (four 250mg tablets) administered orally once daily in combination with Prednisone 5mg administered orally twice daily. XBIRA tablets must be taken on an empty stomach. No food should be consumed for at least 2 hours before the dose of XBIRA tablets is taken and for at least 1 hour after the dose of XBIRA tablets is taken. The tablets should be swallowed whole with water and not to be crushed or chewed. It is highly advisable to administer the drug under strict medical supervision and advice. Expert advice FOR XBIRA: Abiraterone acetate must be taken at least one hour before or two hours after eating and never with food. Men who take abiraterone acetate should always use effective birth control measure when having physical relationship with a woman who is or may become pregnant. You must inform your doctor or dentist that you take abiraterone acetate before receiving any medical or dental care, emergency care, or surgery. Before you take abiraterone acetate tell your doctor if you have high blood sugar, swelling in the feet, ankles, or legs or any effects on your bones or have taken a medicine known as ketoconazole in the past for prostate cancer. Contact your doctor if you experience any bone pain. An increased occurrence of bone fractures has been reported in patients using abiraterone acetate.